Adenosine Receptor Agonist

LUF6096 (Standard) is the analytical standard of LUF6096 (HY-10915). This product is intended for research and analytical applications. LUF6096, a potent allosteric enhancer of the adenosine A3 receptor, is able to allosterically enhance agonist binding. LUF6096 shows low orthosteric affinity for any of the adenosine receptors. LUF6096 shows protective effects in myocardial ischemia/reperfusion injury.

(±)-5'-Chloro-5'-deoxy-ENBA is an agonist of A1AR. (±)-5'-Chloro-5'-deoxy-ENBA produces hypothermia in mice.

N6-Ethyladenosine (Standard) is the analytical standard of N6-Ethyladenosine (HY-111809). This product is intended for research and analytical applications. N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with K_is of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively.

LUF5831 is a non-adenosine agonist with an affinity of K_i=18 nM for adenosine A1 receptor.

N6-Benzyladenosine (Standard) (Benzyladenosine (Standard)) is the analytical standard of N6-Benzyladenosine (HY-N7844). This product is intended for research and analytical applications. N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma-.

PD 117519 (Standard) is the analytical standard of PD 117519 (HY-100032). This product is intended for research and analytical applications. PD 117519 (CI947) is an A2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models.

Binodenoson (Standard) is the analytical standard of Binodenoson (HY-106450). This product is intended for research and analytical applications. Binodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging.

Inosine-13C3 is a ¹³C-labeled Inosine that can be used in pharmacokinetic studies of Inosine. Inosine is an agonist of adenosine receptors A₁R and A_2AR with anti-inflammatory immunomodulatory, antinociceptive and neuroprotective effects.

Namodenoson (Standard) is the analytical standard of Namodenoson. This product is intended for research and analytical applications. Namodenoson (CF-102) is a selective A3 adenosine receptor (A3AR) agonist (K_i=0.33 nM). Namodenoson displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively.

N6-(2-Phenylethyl)adenosine (Standard) (N6-Phenethyladenosine (Standard)) is the analytical standard of N6-(2-Phenylethyl)adenosine (HY-101854). This product is intended for research and analytical applications. N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine), an adenosine derivative, is a potent adenosine receptors (AR) agonist with K_i values of 11.8 nM, 30.1 nM, 0.63 nM for rat A1AR, human A1AR and hA3AR, respectively.

CVT-2759 analog (compound 15) is a partial agonist of A1 adenosine receptor (K_i=167 nM) and can be used for the study of cardiac arrhythmias.

CCPA (2-Chloro-N6-cyclopentyladenosine (Standard)) is the analytical standard of CCPA (HY-103185). This product is intended for research and analytical applications. CCPA (2-Chloro-N6-cyclopentyladenosine) a highly selective A1 adenosine receptors agonist with a K_i of 0.4 nM. CCPA inhibits adenylate cyclase with an IC₅₀ of 33 nM. CCPA exhibits anti-seizure and cardiacprotective activity. CCPA can be used for the research of seizure and myocardial infarction.

N6-Cyclopentyladenosine (Standard) is the analytical standard of N6-Cyclopentyladenosine (HY-103181). This product is intended for research and analytical applications. N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with K_i values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively. N6-cyclopentyladenosine increases Apoptosis. N6-Cyclopentyladenosine has antitumor activity against leukemia. N6-cyclopentyladenosine improves 5-fluorouracil (HY-90006)-induced hematopoietic damage, regulates sleep, and delays Aminophylline-induced clonic epileptic seizures.

BAY 60-6583 (Standard) is the analytical standard of BAY 60-6583. This product is intended for research and analytical applications. BAY 60-6583 is a potent and high-affinity agonist of adenosine A2B receptor (EC50?= 3 nM) over A1, A2A, and A3 receptors. BAY 60-6583 binds to mouse, rabbit, and dog A2BAR with Ki values of 750 nM, 340 nM and 330 nM, respectively. BAY 60-6583 has a cardioprotective effect in a myocardial ischemia model.

Adenosine receptor agonist 1 (compound 6m) is an A3 adenosine receptor (AR) partial agonist with K_i value of 6.7 nM.

N-(7H-Purin-6-yl)acetamide (Compound 25) is a selective adenosine receptor (AdeR) agonist with a K_i value of 0.515 μM for the human adenosine receptor and a K_i value of 2.85 μM for the rat adenosine receptor. N-(7H-Purin-6-yl)acetamide is promising for research of adenosine receptor function, pain perception, inflammatory responses, and renal function.

GW 328267 is an A2A receptor agonist. GW 328267 can be used for research of asthma, COPD and upper respiratory inflammatory disease.

5'-N-Ethylcarboxamidoadenosine (Standard) is the analytical standard of 5'-N-Ethylcarboxamidoadenosine. This product is intended for research and analytical applications. 5'-N-Ethylcarboxamidoadenosine (NECA) is a nonselective adenosine receptor agonist.

UP202-56 is an adenosine analogue, which is an adenosinergic agonist.